2021 Conference USA Leaders Penalties - Games in August/September Only through 01/10/2022
| Name | G | Pen. | Yards | Pen./G | Yards/G | |
|---|---|---|---|---|---|---|
| 1 | UTSA | 4 | 16 | 164 | 4.0 | 41.0 |
| 2 | Louisiana Tech | 4 | 26 | 177 | 6.5 | 44.3 |
| 3 | Charlotte | 4 | 25 | 197 | 6.3 | 49.3 |
| 3 | Western Kentucky | 3 | 22 | 148 | 7.3 | 49.3 |
| 5 | Florida Atlantic | 4 | 27 | 200 | 6.8 | 50.0 |
| 6 | Southern Mississippi | 4 | 27 | 219 | 6.8 | 54.8 |
| 7 | Rice | 4 | 29 | 225 | 7.3 | 56.3 |
| 8 | Florida International | 4 | 25 | 230 | 6.3 | 57.5 |
| 9 | Old Dominion | 4 | 29 | 246 | 7.3 | 61.5 |
| 10 | Middle Tennessee | 4 | 28 | 250 | 7.0 | 62.5 |
| 11 | Marshall | 4 | 27 | 257 | 6.8 | 64.3 |
| 12 | North Texas | 4 | 32 | 271 | 8.0 | 67.8 |
| 13 | UAB | 4 | 38 | 353 | 9.5 | 88.3 |
| 14 | UTEP | 4 | 38 | 382 | 9.5 | 95.5 |