2021 Conference USA Leaders All Purpose - Games in December/January Only through 01/10/2022
| Name | Team | Yr | Pos | G | Rush | Recv. | Punt Ret. | Kick Ret. | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Beanie Bishop | Western Ky | SO | DB | 2 | 0 | 0 | 0 | 196 | 7 | 196 | 28.0 | 98.0 |
| 2 | LaMareon James | ODU | FR | CB | 1 | 0 | 0 | 0 | 134 | 3 | 134 | 44.7 | 134.0 |
| 3 | Tyrin Smith | UTEP | SO | WR | 1 | 0 | 61 | 0 | 64 | 6 | 125 | 20.8 | 125.0 |
| 4 | Jakairi Moses | Western Ky | SO | RB | 2 | 9 | 0 | 0 | 31 | 6 | 40 | 6.7 | 20.0 |
| 5 | John Cook | ODU | FR | LB | 1 | 0 | 0 | 0 | 27 | 2 | 27 | 13.5 | 27.0 |
| 6 | Jaylin Lane | MTSU | FR | WR | 1 | 26 | 64 | 25 | 22 | 14 | 137 | 9.8 | 137.0 |
| 6 | Shadeed Ahmed | Marshall | SO | WR | 1 | 0 | 27 | 0 | 22 | 3 | 49 | 16.3 | 49.0 |
| 8 | Jayden Harrison | Marshall | SO | WR | 1 | 0 | 6 | 0 | 20 | 2 | 26 | 13.0 | 26.0 |
| 9 | Roderic Burns | N Texas | SO | WR | 1 | 0 | 87 | 0 | 19 | 5 | 106 | 21.2 | 106.0 |
| 9 | Justin Garrett | UTEP | SR | WR | 1 | 12 | 26 | -5 | 19 | 5 | 52 | 10.4 | 52.0 |
| 11 | Jermaine Brown Jr. | UAB | JR | RB | 1 | 47 | 18 | 0 | 15 | 11 | 80 | 7.3 | 80.0 |