2020 Big 12 Conference Leaders Long All Purpose Plays - Games at Home Only through 01/11/2021
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| Name | Team | Yr | Pos | G | Yards | Yards | Yards | Yards | Yards | Yards | Yards | |
| 1 | Trestan Ebner | Baylor | SR | RB | 4 | 10 | 6 | 2 | 2 | 2 | 2 | 1 |
| 1 | Kene Nwangwu | Iowa State | SR | RB | 6 | 6 | 3 | 2 | 2 | 1 | 1 | 0 |
| 3 | Tarik Black | Texas | SR | WR | 5 | 3 | 1 | 1 | 1 | 1 | 0 | 0 |
| 3 | LD Brown | Okla St | SR | RB | 5 | 2 | 1 | 1 | 1 | 0 | 0 | 0 |
| 3 | Leddie Brown | WVU | JR | RB | 5 | 6 | 1 | 1 | 1 | 1 | 1 | 0 |
| 3 | Derius Davis | TCU | JR | WR | 6 | 3 | 2 | 2 | 1 | 1 | 0 | 0 |
| 3 | Max Duggan | TCU | SO | QB | 6 | 4 | 3 | 1 | 1 | 1 | 1 | 0 |
| 3 | Zach Evans | TCU | FR | RB | 5 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 3 | Velton Gardner | Kansas | SO | RB | 3 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 3 | Will Howard | Kansas St | FR | QB | 5 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 3 | Xavier Hutchinson | Iowa State | JR | WR | 6 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 3 | Quentin Johnston | TCU | FR | WR | 6 | 4 | 3 | 2 | 1 | 1 | 0 | 0 |
| 3 | Travis Koontz | Texas Tech | SR | TE | 5 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 3 | Kenny Logan Jr. | Kansas | SO | S | 4 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 3 | Kendre Miller | TCU | FR | RB | 6 | 2 | 1 | 1 | 1 | 1 | 1 | 0 |
| 3 | Briley Moore | Kansas St | SR | TE | 4 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 3 | Joshua Moore | Texas | SO | WR | 5 | 2 | 2 | 1 | 1 | 1 | 0 | 0 |
| 3 | Myles Price | Texas Tech | FR | WR | 5 | 3 | 2 | 1 | 1 | 1 | 0 | 0 |
| 3 | Tre Sterling | Okla St | JR | S | 5 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 3 | SaRodorick Thompson | Texas Tech | SO | RB | 6 | 3 | 2 | 1 | 1 | 1 | 0 | 0 |
| 3 | Deuce Vaughn | Kansas St | FR | RB | 5 | 4 | 2 | 1 | 1 | 1 | 0 | 0 |