2016 American Athletic Conference Leaders Interceptions - Games in August/September Only through 01/09/2017
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Jordan Wyatt | SMU | SO | DB | 4 | 3 | 62 | 1 | 0.75 |
| 1 | Howard Wilson | Houston | SO | CB | 5 | 3 | 28 | 1 | 0.60 |
| 1 | Parry Nickerson | Tulane | JR | CB | 4 | 2 | 133 | 1 | 0.50 |
| 1 | Tyrell Gilbert | Cincinnati | SO | S | 4 | 2 | 84 | 1 | 0.50 |
| 1 | Jonathan Wilson | Memphis | FR | DL | 3 | 1 | 61 | 1 | 0.33 |
| 1 | Genard Avery | Memphis | JR | LB | 3 | 1 | 28 | 1 | 0.33 |
| 1 | Kolton Shindelar | Tulsa | JR | DE | 4 | 1 | 65 | 1 | 0.25 |
| 1 | Jesse Brubaker | Tulsa | JR | DT | 4 | 1 | 24 | 1 | 0.25 |
| 1 | Steven Taylor | Houston | SR | OLB | 5 | 1 | 74 | 1 | 0.20 |