2016 Atlantic Coast Conference Leaders Sacks - Games vs. FBS Power 5 Conference Teams Only through 01/09/2017
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Florida State | 11 | 44.0 | 256 | 4.00 |
| 2 | Wake Forest | 9 | 31.0 | 194 | 3.44 |
| 3 | Clemson | 13 | 43.0 | 282 | 3.31 |
| 4 | Boston College | 9 | 29.0 | 224 | 3.22 |
| 5 | Pittsburgh | 11 | 35.0 | 217 | 3.18 |
| 6 | North Carolina State | 9 | 25.0 | 184 | 2.78 |
| 7 | Miami (Florida) | 9 | 24.0 | 154 | 2.67 |
| 8 | Duke | 9 | 21.0 | 112 | 2.33 |
| 9 | Louisville | 10 | 23.0 | 187 | 2.30 |
| 10 | Virginia Tech | 11 | 24.0 | 152 | 2.18 |
| 11 | North Carolina | 11 | 21.0 | 146 | 1.91 |
| 12 | Virginia | 9 | 16.0 | 73 | 1.78 |
| 13 | Georgia Tech | 11 | 15.0 | 75 | 1.36 |
| 14 | Syracuse | 8 | 8.0 | 50 | 1.00 |