2016 Conference USA Leaders Sacks - Games vs. FBS non-Power 5 Conference Teams Only through 01/09/2017
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Louisiana Tech | 11 | 37.0 | 221 | 3.36 |
| 2 | Old Dominion | 11 | 29.0 | 206 | 2.64 |
| 3 | Marshall | 9 | 22.0 | 115 | 2.44 |
| 4 | Southern Mississippi | 10 | 24.0 | 163 | 2.40 |
| 5 | Western Kentucky | 11 | 25.0 | 153 | 2.27 |
| 6 | North Texas | 11 | 23.0 | 160 | 2.09 |
| 7 | Florida Atlantic | 9 | 18.0 | 103 | 2.00 |
| 8 | Rice | 9 | 17.0 | 97 | 1.89 |
| 9 | UTSA | 10 | 18.0 | 124 | 1.80 |
| 9 | Middle Tennessee | 10 | 18.0 | 111 | 1.80 |
| 11 | Charlotte | 10 | 13.0 | 71 | 1.30 |
| 11 | Florida International | 10 | 13.0 | 57 | 1.30 |
| 13 | UTEP | 10 | 10.0 | 75 | 1.00 |