2016 Conference USA Leaders Rushing Defense - Games vs. FBS non-Power 5 Conference Teams Only through 01/09/2017
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Western Kentucky | 11 | 329 | 1041 | 3.16 | 11 | 29.91 | 94.64 |
| 2 | UTSA | 10 | 364 | 1579 | 4.34 | 18 | 36.40 | 157.90 |
| 3 | Charlotte | 10 | 336 | 1352 | 4.02 | 20 | 33.60 | 135.20 |
| 3 | Old Dominion | 11 | 423 | 1795 | 4.24 | 20 | 38.45 | 163.18 |
| 5 | Louisiana Tech | 11 | 402 | 1589 | 3.95 | 22 | 36.55 | 144.45 |
| 5 | Rice | 9 | 348 | 1754 | 5.04 | 22 | 38.67 | 194.89 |
| 5 | Marshall | 9 | 370 | 1849 | 5.00 | 22 | 41.11 | 205.44 |
| 5 | UTEP | 10 | 397 | 2216 | 5.58 | 22 | 39.70 | 221.60 |
| 9 | Florida Atlantic | 9 | 410 | 2187 | 5.33 | 23 | 45.56 | 243.00 |
| 10 | Southern Mississippi | 10 | 349 | 1659 | 4.75 | 24 | 34.90 | 165.90 |
| 10 | Florida International | 10 | 360 | 1900 | 5.28 | 24 | 36.00 | 190.00 |
| 12 | North Texas | 11 | 513 | 2702 | 5.27 | 26 | 46.64 | 245.64 |
| 13 | Middle Tennessee | 10 | 441 | 1912 | 4.34 | 28 | 44.10 | 191.20 |